To date the 60x60 project has created 7 themed mixes of the project. These mixes have ranged from regional themes to political themes. Some mixes are one time events, others are being created yearly in tandem with the International Mix. Current active mixes for 60x60 include: Canada Mix, Pacific Rim Mix, Midwest Mix, UK Mix, and the Evolution Mix. Past mixes have included: New York Minute Mix and the Munich Mix on Oppression and Totalitarianism.
In conjunction with the ideals of Vox Novus, the mission of the 60x60 project is to promote new music. The project is specifically designed to include a large number of composers and present their music to audiences around. The project has taken a "grass-roots" philosophy with much of its success due to its collaborators, hosts, and director who are composers themselves.